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Editorial Coexisting linear and disseminated drug eruption: a clinical clue to the understanding of the genetic basis of drug eruptionsRudolf HAPPLE, Isaak EFFENDY 
Review EMLA anaesthetic cream for sharp leg ulcer debridement: a review of the clinical evidence for analgesic efficacy and tolerabilityWolfgang VANSCHEIDT, Zhabeez SADJADI, Stefan LILLIEBORG
Genes and skin Familial occurrence of nevus sebaceus of Jadassohn: another case of paradominant inheritance?Luigi LAINO, Maurice A.M. van STEENSEL, Daniele INNOCENZI, Germana CAMPLONE
Investigative Reports Reduced levels of glutathione S-transferases in patch test reactions to dithranol and sodium lauryl sulphate as demonstrated by quantitative immunocytochemistry: evidence for oxidative stress in acute irritant contact dermatitisCarolyn M. WILLIS, Lezlie E. BRITTON, Louise REICHE, John D. WILKINSON
Immunohistochemical detection of interferon-gamma-producing cells in dermatophytosis Tetsuya KOGA, Hong DUAN, Kazunori URABE, Masutaka FURUE
Detection of cutaneous varicella zoster virus infections by immunofluorescence versus PCR Guntram D. BEZOLD, Monika E. LANGE, Helmut GALL, Ralf U. PETER
Induction of matrix metalloproteinase-1 in in vitro experimental wound model using a novel three-dimensional culture system Masatoshi ABE, Chie KAN, Khine Khine ZAW, Osamu ISHIKAWA
Therapy Juvenile generalized circinate pustular psoriasis treated with oral cyclosporin AUwe WOLLINA, Veronika FUNFSTUCK
Clinical Reports Hyperpigmentation of the distal phalanx in healthy Caucasian neonatesEmmanuelle CRESPEL, Patrice PLANTIN, Patricia SCHOENLAUB, Monique BLAYO, Christelle QUEINNEC, Lucas BROUSSINE
Linear drug eruption Remedios ALFONSO, Isabel BELINCHON
Inflammatory cutaneous metastasis from laryngeal carcinoma Ugo BOTTONI, Daniele INNOCENZI, T.J. MANNOORANPARAMPIL, Antonio RICHETTA, Maura DEL GIUDICE, Stefano CALVIERI
Discoid lupus erythematosus developing in areas where fragments of windshield glass had become embedded in the skin Hiroaki UEKI, Kentaro OMORI
Skin metastasis of breast cancer clinically undistinguished from amyopathic dermatomyositis Mariko SEISHIMA, Hideki SHIMIZU, Zuiei OYAMA
Delayed adverse reaction to sodium ioxaglic acid-meglumine Gisèle KANNY, Béatrice MARIE, Bruno HOEN, Philippe TRECHOT, Denise A. MONERET-VAUTRIN
Subcutaneous nodules following treatment with aluminium-containing allergen extracts Eduardo NAGORE, Jorge A. MARTINEZ-ESCRIBANO, Agustin TATO, Vicente SABATER, Juan J. VILATA
Pemphigus of the eyelids Mariko SEISHIMA, Zuiei OYAMA, Hideki SHIMIZU, Yoshiyuki NAGANAWA, Tomoaki YOSHIMURA, Futoshi YAMAZAKI
Guess what! Dermatofibrosarcoma protuberans presenting as an atrophic red plaqueAdrian C.Y. SEE, Steven S. KOSSARD, Dédée F. MURRELL
B-cell acute lymphoblastic leukemia with aleukemic leukemia cutis Hiroshi KISHIMOTO, Yoshihiko FURUI, Kiyoshi NISHIOKA
Perifolliculitis capitis abscedens et suffodiens P. MOSCATELLI, D. IPPOLITI, F. BERGAMO, P. PIAZZA
Classic Kaposi's sarcoma G. SAPIENZA, M.R. NASCA, F. DINOTTA, G. MICALI
CME articles Understanding nail disordersRobert BARAN, Paul KECHIJIAN
Meeting report Photoaging: A Daily Care IntroductionAndré ROUGIER
What is photoaged skin? James LEYDEN
Dyspigmentation of aged skin Jean-Paul ORTONNE
The role of UVA rays in skin aging Jean KRUTMANN
Topical vitamin C in the treatment of photoaged skin Philippe HUMBERT
Conclusions and perspectives André ROUGIER
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